Infantile polymyoclonus: Its occurrence in second cousins.

Area of Science:

• Neurology
• Genetics

Background:

• Infantile polymyoclonus is an exceedingly rare neurological disorder.
• Previously reported cases of infantile polymyoclonus have been sporadic.

Observation:

• This report describes two second cousins diagnosed with infantile polymyoclonus.
• The affected individuals are members of the same family.

Findings:

• The co-occurrence of infantile polymyoclonus in two related individuals suggests a possible genetic basis for the disorder.
• This observation contrasts with the typically sporadic nature of previously documented cases.

Implications:

• The findings indicate that genetic transmission may play a role in infantile polymyoclonus.
• Further investigation into family pedigrees is crucial for understanding the inheritance patterns of this rare condition.