Neural mediation of compensatory adrenal growth
Related Experiment Video
Updated: Oct 23, 2026

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
Published on: October 2, 2018
Abstract:
Spinal cord hemisection between T2 and T3 inhibits compensatory adrenal growth when the contralateral but not the ipsilateral adrenal is removed (p less than 0.01). Pretreatment of left adrenals with 1 or 2% lidocaine, but not with saline, before removal inhibits compensatory right adrenal growth that is normally observed at 12 h (p less than 0.01). These results provide further functional evidence that both afferent and efferent neural elements mediate adrenal growth after unilateral adrenalectomy.
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