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The Lewontin and Krakauer test on quantitative characters.

C B Krimbas

    Genetics
    |October 1, 1976
    PubMed
    Summary

    Lewontin and Krakauer's test can be extended to analyze quantitative genetic traits lacking significant dominance or epistasis. This research explores experimental designs and addresses estimation errors for the F statistic in such applications.

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    Area of Science:

    • Quantitative genetics
    • Population genetics

    Background:

    • Lewontin and Krakauer's test is a standard method for detecting selection.
    • Its application is typically limited to qualitative traits.

    Purpose of the Study:

    • To demonstrate the applicability of Lewontin and Krakauer's test to quantitative traits.
    • To discuss experimental designs and estimation errors for this extended application.

    Main Methods:

    • Theoretical extension of Lewontin and Krakauer's test.
    • Discussion of experimental design principles.
    • Analysis of F-statistic estimation error.

    Main Results:

    • Lewontin and Krakauer's test is adaptable for quantitative traits without significant dominance or epistatic genetic variances.
    • The study outlines suitable experimental designs for this purpose.

    Conclusions:

    • The generalized Lewontin and Krakauer's test offers a new tool for analyzing quantitative genetic variation.
    • Further research can explore its power in detecting selection on quantitative traits.

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