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Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
How do peptide synthetases generate structural diversity?
1Philipps-Universität Marburg, Fachbereich Chemie/Biochemie, Germany.
Chemistry & Biology
|February 18, 1999
Abstract:
Many low-molecular-weight peptides of microbial origin are synthesized nonribosomally on large multifunctional proteins, termed peptide synthetases. These enzymes contain repeated building blocks in which several defined domains catalyze specific reactions of peptide synthesis. The order of these domains within the enzyme determines the sequence and structure of the peptide product.
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