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Methodological issues in estimating the cost of epilepsy.
C E Begley1, J F Annegers, D R Lairson
1The University of Texas, Houston, School of Public Health, 77225, USA.
Epilepsy Research
|February 18, 1999
Summary
The cost of epilepsy in the USA has not been comprehensively studied since 1975. This review examines epilepsy cost research and methodological issues, highlighting a 1993 study update.
Area of Science:
- Medical Economics
- Public Health
- Epilepsy Research
Background:
- Managed care and cost containment have increased interest in epilepsy costs.
- The last comprehensive US cost study was in 1975, estimating $3.6 billion nationally.
- Previous studies show wide cost variations ($6,000-$15,000 per patient/year).
Purpose of the Study:
- To review the state of epilepsy cost-of-illness (COI) research.
- To discuss methodological challenges in COI studies.
- To describe a comprehensive US study initiated in 1993.
Main Methods:
- Literature review of epilepsy cost-of-illness (COI) studies.
- Analysis of methodological issues in existing research.
- Description of a large-scale US study updating 1975 estimates.
Main Results:
- Significant increases in interest in epilepsy cost data.
- Variability in direct and indirect cost percentages across studies.
- A comprehensive US study initiated in 1993 to provide updated estimates.
Conclusions:
- Need for updated and standardized epilepsy cost-of-illness research.
- Importance of addressing methodological issues for accurate cost assessment.
- Recommendations for future research methods in epilepsy economics.
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