Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple sclerosis and the urologist.

S E Litwiller1, E M Frohman, P E Zimmern

  • 1Department of Urology, University of Texas Southwestern Medical Center, Dallas, USA.

The Journal of Urology
|February 18, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Enterococcus faecalis</i> Influences the Transcription and Metabolism of Pathogenic <i>Escherichia coli</i> when Grown in Co-Culture.

bioRxiv : the preprint server for biology·2026
Same author

Usefulness of an algebraic fitting of nomograms allowing evaluation detrusor contractility in women.

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2016
Same author

Detrusor contractility in women: Influence of ageing and clinical conditions.

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2016
Same author

Extended interval dosing of natalizumab in multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry·2016
Same author

Expansion of CD27high plasmablasts in transverse myelitis patients that utilize VH4 and JH6 genes and undergo extensive somatic hypermutation.

Genes and immunity·2013
Same author

Evidence-based guideline: clinical evaluation and treatment of transverse myelitis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

Neurology·2011

Multiple sclerosis (MS) frequently causes genitourinary issues, impacting bladder function and sexual health. Early urological involvement is crucial for managing these significant, though rarely life-threatening, MS complications.

Area of Science:

  • Neurology
  • Urology
  • Medical Research

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease.
  • MS affects the central nervous system, leading to a wide range of symptoms.
  • Genitourinary dysfunction is a common but often overlooked complication of MS.

Purpose of the Study:

  • To provide an updated overview of neurological and urological approaches to multiple sclerosis.
  • To detail the pathology, physiology, and genitourinary effects of MS.
  • To outline diagnostic and treatment strategies for neurological and urological manifestations in MS patients.

Main Methods:

  • Conducted a comprehensive literature search of MEDLINE and manual bibliography review.
  • Included peer-reviewed articles on neurological and urological aspects of MS.

Related Experiment Videos

  • Performed a meta-analysis of urodynamic findings from 22 studies (1,882 patients).
  • Main Results:

    • Most MS patients experience genitourinary symptoms (urgency, incontinence, retention).
    • Urodynamic findings include detrusor hyperreflexia (62%), detrusor-sphincter dyssynergia (25%), and hypocontractility (20%).
    • Sexual dysfunction affects up to 80% of men and 72% of women; renal deterioration is rare (<1%).

    Conclusions:

    • Genitourinary complications of MS cause significant morbidity and patient distress.
    • Despite advances in MS management, urological symptoms require active, multidisciplinary care.
    • Urologist involvement is essential for comprehensive MS patient management.