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Orally administered proteases in aesthetic surgery.
Aesthetic Plastic Surgery
|February 18, 1999
Summary
Systemic enzyme therapy using proteases effectively reduced post-surgery swelling and pain after eyelid blepharoplasty. This treatment option showed no adverse effects and is safe for patients with common health conditions.
Area of Science:
- Plastic Surgery
- Pharmacology
- Biochemistry
Background:
- Aesthetic surgery recovery times are increasingly scrutinized.
- Systemic enzyme therapy offers potential benefits for inflammation and healing.
- Previous studies indicate efficacy in treating secondary lymphedema.
Purpose of the Study:
- To compare the efficacy of protease therapy versus standard treatments for post-blepharoplasty recovery.
- To evaluate the incidence of hematoma, edema, and pain.
Main Methods:
- A randomized trial involving 40 patients undergoing upper eyelid blepharoplasty.
- One group received proteases (Wobenzym drg).
- The control group received systemic antiedema and hemostyptic therapy (Dicynone drg and Reparil drg).
Main Results:
- Protease therapy demonstrated effectiveness in managing post-operative sequelae.
- No undesirable side effects were reported with protease use.
- Protease therapy appears safe for patients with cardiovascular, hepatic, or renal comorbidities.
Conclusions:
- Systemic protease therapy is a viable and safe option for accelerating recovery after aesthetic eyelid surgery.
- This approach may reduce common complications like hematoma, edema, and pain.
- Further research can explore broader applications in plastic surgery recovery.