Fatal Serratia marcescens meningitis and myocarditis in a patient with an indwelling urinary catheter
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Updated: Oct 24, 2026

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
J S Johnson1, J Croall, J S Power
1Department of Histopathology, Hope Hospital, Salford, UK.
Abstract:
Serratia marcescens is commonly isolated from the urine of patients with an indwelling urinary catheter and in the absence of symptoms is often regarded as a contaminant. A case of fatal Serratia marcescens septicaemia with meningitis, brain abscesses, and myocarditis discovered at necropsy is described. The patient was an 83 year old man with an indwelling urinary catheter who suffered from several chronic medical conditions and from whose urine Serratia marcescens was isolated at the time of catheterisation. Serratia marcescens can be a virulent pathogen in particular groups of patients and when assessing its significance in catheter urine specimens, consideration should be given to recognised risk factors such as old age, previous antibiotic treatment, and underlying chronic or debilitating disease, even in the absence of clinical symptoms.
Insights
Serratia marcescens in catheter urine is often a contaminant. However, this case shows it can cause fatal septicaemia, meningitis, and myocarditis, especially in elderly patients with chronic conditions.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Clinical Pathology
Background:
- Serratia marcescens is frequently found in catheterized patients' urine.
- It's often dismissed as contamination if no symptoms are present.
Observation:
- An 83-year-old male with an indwelling urinary catheter and chronic conditions had Serratia marcescens isolated from urine.
- The patient later developed fatal septicaemia with meningitis, brain abscesses, and myocarditis.
Findings:
- Serratia marcescens can be a virulent pathogen, not just a contaminant.
- Risk factors include old age, prior antibiotic use, and chronic illness.
Implications:
- Clinicians should consider Serratia marcescens' pathogenic potential in at-risk patients, even without symptoms.
- Careful assessment of catheter urine is crucial for identifying serious infections.
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