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Association between serotonin transporter gene polymorphism and anxiety-related traits
S Katsuragi1, H Kunugi, A Sano
1Department of Neuropsychiatry, Oita Medical University, Japan.
Biological Psychiatry
|February 19, 1999
Abstract
Background:
Polymorphism in the serotonin transporter promoter gene has been recently reported to be associated with the personality trait known as anxiety-related traits. We have attempted to replicate these findings in 101 healthy Japanese subjects.
Methods:
The personality traits of the subjects were assessed with the tridimensional personality questionnaire.
Results:
An association was observed in the present study between individuals grouped according to the transporter gene and harm avoidance scores.
Conclusions:
These data supported that there was an association between the serotonin transporter gene and anxiety.