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Steroid-responsive multifocal demyelinating neuropathy with central involvement
R Liguori1, R Rizzi, R Vetrugno
1Institute of Neurology, University of Bologna, Italy.
Muscle & Nerve
|February 19, 1999
Abstract:
We describe 2 patients with associated central and peripheral demyelination. Electrophysiological studies revealed a demyelinating polyneuropathy with sensory and motor conduction blocks. Visual evoked potentials were abnormal. Motor evoked potentials showed abnormal central conduction time in 1 patient. Magnetic resonance imaging revealed regions of abnormal high signal in the spinal cord and brain; sural nerve biopsy disclosed a demyelinating neuropathy. Both patients showed clinical and electrophysiological improvement after steroid therapy.