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[Cytomegalovirus enteritis in AIDS. 2 cases].

M L Uffredi1, S Fournier, M Lemann

  • 1Clinique des Maladies Infectieuses et Tropicales, Hôpital Saint-Louis, Paris.

Presse Medicale (Paris, France : 1983)
|February 23, 1999
PubMed
Summary
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Cytomegalovirus (CMV) infection in AIDS patients rarely affects only the small bowel. Early diagnosis and treatment are crucial for managing CMV enteritis, though outcomes can be poor.

Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Virology

Background:

  • Cytomegalovirus (CMV) infection is a significant opportunistic infection in individuals with Acquired Immunodeficiency Syndrome (AIDS).
  • CMV manifestations typically involve multiple organs, making isolated small bowel involvement uncommon.

Observation:

  • Two human immunodeficiency virus (HIV)-positive patients presented with CMV infection exclusively localized to the small intestine.
  • These patients experienced frequent recurrences of CMV enteritis despite receiving medical treatment.

Findings:

  • Clinical symptoms including diarrhea, fever, vomiting, and abdominal pain are indicative of CMV enteritis in AIDS patients.
  • Diagnosis is confirmed through small bowel imaging studies and histopathological examination of biopsy samples.

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  • Treatment strategies involve a combination of intravenous anti-CMV medications and surgical intervention, such as partial bowel resection.

    • Implications:

    • Prompt recognition of CMV enteritis is essential for timely intervention in AIDS patients.
    • The condition's potential for recurrence and late diagnosis contributes to a generally unsatisfactory prognosis.
    • Further research into optimizing treatment protocols and early diagnostic methods for CMV enteritis is warranted.