Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sickle-cell dactylitis.

V T Worrall, V Butera

    The Journal of Bone and Joint Surgery. American Volume
    |December 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Sickle-cell dactylitis, a painful swelling of the digits in children with sickle-cell anemia, presents with distinct clinical and radiographic features. Early recognition of this syndrome is crucial to avoid misdiagnosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Paralytic instability of the hip in myelomengoceles.

    Clinical orthopaedics and related researchยท1977
    See all related articles

    Area of Science:

    • Pediatrics
    • Hematology
    • Radiology

    Background:

    • Sickle-cell dactylitis is a common early manifestation of sickle-cell disease in children.
    • It often presents before the definitive diagnosis of sickle-cell disease is made.

    Purpose of the Study:

    • To better define the presentation, roentgenographic features, and clinical course of sickle-cell dactylitis.
    • To improve diagnostic accuracy and reduce misdiagnosis.

    Main Methods:

    • Retrospective review of medical records of nine children diagnosed with sickle-cell anemia and dactylitis.
    • Analysis of clinical signs, symptoms, and radiographic findings.

    Main Results:

    • Average age at diagnosis was 18 months; dactylitis preceded sickle-cell disease diagnosis in 5 cases.

    Related Experiment Videos

  • Clinical signs (swelling, tenderness, fever, leukocytosis) resolved within 5-31 days.
  • Radiographic features (periosteal new-bone, intramedullary densities) appeared within 7-14 days and resolved within 2-3 months.

    • Conclusions:

    • Sickle-cell dactylitis has characteristic clinical and radiographic features that aid in diagnosis.
    • Increased familiarity with this syndrome can prevent frequent misdiagnoses.