Prevalence of latex sensitivity among patients with chronic renal failure: a new risk group?

Latex has been documented as causing immediate hypersensitivity reactions in forms ranging from contact urticaria to severe anaphylaxis. The prevalence of latex allergy appears to be higher in certain risk groups as a result of increased exposure or an increased intrinsic predilection for atopy. The purpose of the present study was to assess latex sensitivity in a large group of patients who are undergoing regular dialysis because of chronic renal failure (CRF) and to evaluate the relationship between latex sensitivity and skin prick test (SPT) responses to fruit allergens. Of the 268 patients tested, 3 subjects (1.1%) were found to have latex sensitivity via SPT. Although atopy was not demonstrated in any SPT positive subjects, there appears to be a considerable degree of crossreactivity between latex and certain fruit allergens which can be suggested as one subtext in the SPT positive patients. In conclusion, CRF patients with no history of hypersensitivity reactions should not be considered at risk for developing latex sensitization despite their frequent exposure.