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New quinoxaline 1,4-di-N-oxides for treatment of tuberculosis
Y Sainz1, M E Montoya, F J Martínez-Crespo
1Centro de Investigación en Farmacobiología Aplicada, Universidad de Navarra, Pamplona, Spain.
Arzneimittel-Forschung
|February 24, 1999
Abstract:
Some quinoxaline 1,4-di-N-oxides derivatives with very different substituents in 2, 3, 6 and 7 positions have been synthesized in order to obtain new hypoxia selective agents. Some of these products have been tested as antituberculosis agents and very interesting results have been obtained from the first screening.