Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Delayed hypersensitivity to enoxaparin.

R Cabañas1, M T Caballero, M C López-Serrano

  • 1Allergy Department, Hospital La Paz, Madrid, Spain.

Journal of Investigational Allergology & Clinical Immunology
|February 24, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Capacitive heating devices for therapeutic hyperthermia: a review of essential physical characteristics and challenges.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2026
Same author

Refurbishment and commissioning of a dual-band 23/31 GHz tipping radiometer at potential radio astronomical sites.

The Review of scientific instruments·2025
Same author

Determinants of Disease Activity in Adults With Hereditary Angioedema due to C1-Esterase Inhibitor Deficiency.

Journal of investigational allergology & clinical immunology·2024
Same author

Successful Desensitization to Lenalidomide in Leukocytoclastic Vasculitis.

Journal of investigational allergology & clinical immunology·2024
Same author

Global Lung Initiative as Diagnostic Criteria in Asthma-COPD Overlap Syndrome: Prevalence and Disease Characterization in a Real-Life Asthma Cohort.

Journal of investigational allergology & clinical immunology·2024
Same author

Real-life Experience of Subcutaneous Plasma Derived C1-Inhibitor as Long-term Prophylaxis in HAE-C1INH.

Journal of investigational allergology & clinical immunology·2023
Same journal

Safety, Adherence, and Effectiveness of an Increased Dose of Pollinex Quattro Grass and/or Olive in Real-World Practice.

Journal of investigational allergology & clinical immunology·2026
Same journal

Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Moderate-to-Severe Asthma, Type 2 Inflammation, and Nocturnal Awakenings: The MORPHEO Randomized Controlled Trial.

Journal of investigational allergology & clinical immunology·2026
Same journal

Severe Rituximab-Induced Cytokine Release Syndrome After Desensitization Successfully Treated With Tocilizumab: A Case Report.

Journal of investigational allergology & clinical immunology·2026
Same journal

Dysregulation of Mast Cell Prostaglandin in Food Anaphylaxis.

Journal of investigational allergology & clinical immunology·2026
Same journal

Extract-Negative Cofactor-Dependent Shrimp Anaphylaxis Caused by IgE Reactivity to Insoluble Muscle Proteins.

Journal of investigational allergology & clinical immunology·2026
Same journal

Antibiotic Allergy Labels in Hospitalized Patients: Results of a Multicenter Cross-Sectional Study.

Journal of investigational allergology & clinical immunology·2026
See all related articles

A delayed hypersensitivity reaction to sodium enoxaparin caused itchy skin patches in a patient. Skin biopsy confirmed the reaction, highlighting the need to consider this rare side effect.

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Enoxaparin is a widely used low molecular weight heparin anticoagulant.
  • Adverse reactions to enoxaparin can occur, though delayed hypersensitivity is rare.

Observation:

  • A 65-year-old woman developed itchy, erythematous patches at enoxaparin injection sites 48 hours post-injection.
  • The lesions resolved spontaneously within a week.
  • Previous enoxaparin treatments over 1-3 years did not cause adverse reactions.

Findings:

  • Epicutaneous and skin prick tests for enoxaparin, nadroparin, and heparin were negative.
  • Skin biopsy revealed spongiotic dermatitis, indicative of a delayed hypersensitivity mechanism (Type IV).
  • Female gender, overweight status, and prolonged enoxaparin use were identified as potential risk factors.

Related Experiment Videos

Implications:

  • This case highlights a rare instance of delayed hypersensitivity to enoxaparin.
  • Skin biopsy is crucial for diagnosing such reactions.
  • Clinicians should consider enoxaparin-induced delayed hypersensitivity to avoid underdiagnosis.