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Sleep-disordered breathing in alcoholics.

M S Aldrich1, K J Brower, J M Hall

  • 1University of Michigan Alcohol Research Center, and Department of Neurology, University of Michigan Medical Center, Ann Arbor 48109-0117, USA. maldrich@umich.edu

Alcoholism, Clinical and Experimental Research
|February 24, 1999
PubMed
Summary
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Sleep-disordered breathing, including sleep apnea, is common in older alcoholics and worsens with age. This condition leads to poor sleep, daytime sleepiness, and potential health risks.

Area of Science:

  • Sleep Medicine
  • Addiction Research
  • Pulmonology

Background:

  • Sleep disturbances are prevalent in individuals with a history of alcoholism.
  • Previous research indicated a link between sleep-disordered breathing and age in abstinent alcoholics.

Purpose of the Study:

  • To investigate the prevalence and severity of sleep-disordered breathing in a larger cohort of abstinent alcoholics.
  • To identify factors associated with sleep-disordered breathing in this population.

Main Methods:

  • Polysomnography was used to assess sleep-disordered breathing in 188 abstinent alcoholics and 87 controls.
  • Subjects were stratified by age groups (under 40, 40-59, 60+).

Main Results:

  • Sleep-disordered breathing prevalence increased significantly with age in alcoholics (3% <40, 17% 40-59, 50% 60+).

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  • Sleep-disordered breathing was associated with male sex, increased sleep disruption, nocturnal hypoxemia, and daytime sleepiness.
  • Age and BMI were significant predictors; smoking and drinking duration were not after controlling for age and BMI.
  • Conclusions:

    • Sleep-disordered breathing is a significant contributor to sleep disturbance in older alcoholics, with prevalence increasing with age.
    • This condition, especially with cardiovascular risk factors, may lead to adverse health outcomes in alcoholics.