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Updated: Aug 19, 2026
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Biliary-intestinal bypass in the treatment of obesity: long term follow up
1Department of Surgery, Lycksele Hospital, Sweden.
Objective:
To evaluate the long term outcome after biliary-intestinal bypass for morbid obesity.
Design:
Retrospective study.
Setting:
County hospital, Sweden.
Subjects:
120 consecutive patients operated on between 1977 and 1990.
Interventions:
A variation of jejunoileal bypass in which the excluded bowel was anastomosed to the gallbladder.
Main Outcome Measures:
Weight, concentrations of blood lipids and glucose in blood, results of liver function tests, reversal rates, and complications.
Results:
The mean body mass index was reduced by 39% (from 42 kg/m2 to 26 kg/m2), serum cholesterol and triglyceride concentrations by more than 30%, and fasting blood glucose concentrations by 1 1%. There were no cases of irreversible hepatic failure, diabetes, deaths related to the operation, or progressive renal failure. The incidence of renal calculi increased by a ratio 2.3. The reversal rate/year was 2% (n = 20).
Conclusion:
We conclude that biliary-intestinal bypass may be used to treat cases of obesity associated with seriously high blood lipid concentrations and where gastric restrictive operations are less suitable.
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