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Published on: December 4, 2020
Race/ethnicity, vaginal flora patterns, and pH during pregnancy
R A Royce1, T P Jackson, J M Thorp
1Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill 27599, USA. Rachel_Royce@unc.edu
Objectives:
To investigate the relationship between bacterial vaginosis during pregnancy and black race/ethnicity.
Study Design:
Gram staining was used to evaluate vaginal flora in 842 women at 24 to 29 weeks' gestation.
Results:
Overall, 22.3% of blacks and 8.5% of whites had bacterial vaginosis. Vaginal pH and flora differed significantly by race/ethnicity; blacks were more likely to have pH > or = 4.5, no lactobacilli, small gram-variable and -negative rods, and Mobiluncus compared with whites (odds ratios 1.6, 1.5, 1.4, and 10.6, respectively). Quantity of morphotypes also differed, especially for Mobiluncus. Among women with Mobiluncus present (12.0% of blacks and 1.3% of whites), 73.3% of blacks compared with 40.0% of whites had the highest level. Adjustment for sociodemographics, sexual activity, sexually transmitted diseases, health behavior, and sexual hygiene did not explain these differences.
Conclusion:
We observed race/ethnicity differences in vaginal flora ecology. These differences may ultimately play a role in the larger proportion of preterm deliveries among black women compared with white women.
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