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Related Experiment Videos

Linac radiosurgery for benign meningiomas.

D H Shafron1, W A Friedman, J M Buatti

  • 1Department of Neurosurgery, University of Florida College of Medicine, Gainesville, USA.

International Journal of Radiation Oncology, Biology, Physics
|February 25, 1999
PubMed
Summary

Linac radiosurgery effectively treated benign meningiomas, with no lesions enlarging post-treatment. This study suggests stereotactic radiosurgery is a viable option for meningioma patients.

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Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Oncology

Background:

  • Benign meningiomas are primary tumors of the brain and spine.
  • Treatment options include surgery, radiotherapy, and observation.
  • Stereotactic radiosurgery offers a minimally invasive approach.

Purpose of the Study:

  • To evaluate the outcomes of patients treated with linac radiosurgery for benign meningiomas.
  • To assess tumor control rates and adverse events.
  • To determine the efficacy of radiosurgery as an initial or adjuvant therapy.

Main Methods:

  • Retrospective review of 70 patients with 76 meningiomas treated between 1989 and 1997.
  • Analysis of treatment volumes, peripheral doses, and clinical follow-up.
  • Radiosurgery was either the primary treatment or followed surgery/radiotherapy.

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Main Results:

  • No lesions demonstrated enlargement during the follow-up period.
  • Tumor size reduction was observed in 21 of 48 lesions with at least one year of imaging follow-up.
  • Two patients experienced transient neurological deficits, with doses higher than current recommendations.

Conclusions:

  • Stereotactic radiosurgery shows early promise as an effective treatment for benign meningiomas.
  • Long-term follow-up is essential for a comprehensive evaluation of efficacy.
  • Linac radiosurgery represents a valuable therapeutic option for managing meningiomas.