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Optic nerve hypoplasia with posterior pituitary ectopia: male predominance and nonassociation with breech delivery

M C Brodsky1

  • 1University of Arkansas for Medical Sciences, Little Rock, USA.

American Journal of Ophthalmology
|February 25, 1999
PubMed

Insights

Posterior pituitary ectopia associated with optic nerve hypoplasia predominantly affects boys. This condition does not appear to be linked to breech deliveries in children.

Area of Science:

  • Pediatric Endocrinology
  • Neuro-ophthalmology
  • Developmental Pediatrics

Background:

  • Optic nerve hypoplasia (ONH) is a congenital condition.
  • Posterior pituitary ectopia (PPE) is a rare developmental anomaly.
  • The etiology and associated factors of PPE in ONH are not fully understood.

Purpose of the Study:

  • To investigate the sex distribution in children diagnosed with ONH and PPE.
  • To determine if breech delivery is a risk factor for PPE in children with ONH.

Main Methods:

  • A retrospective analysis was conducted.
  • The study included 12 pediatric patients with confirmed ONH and PPE.
  • Data on sex and delivery history were collected and reviewed.

Main Results:

  • A significant male predominance was observed, with 11 out of 12 patients being boys.
  • None of the patients had a history of uncomplicated vaginal breech delivery.
  • Two patients had a history of breech presentation but were delivered via cesarean section.

Conclusions:

  • Posterior pituitary ectopia in the context of optic nerve hypoplasia demonstrates a strong male predominance.
  • There is no observed association between posterior pituitary ectopia and breech delivery in this patient cohort.
Abstract

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