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Related Experiment Videos

Temperature measurement using echo-shifted FLASH at low field for interventional MRI.

Y C Chung1, J L Duerk, A Shankaranarayanan

  • 1Department of Radiology, Case Western Reserve University and University Hospitals of Cleveland, Ohio 44106, USA.

Journal of Magnetic Resonance Imaging : JMRI
|February 25, 1999
PubMed
Summary

Echo-shifted fast low-angle shot (FLASH) enables accurate temperature monitoring during thermal therapies using low-field interventional MRI. This technique provides rapid, reliable temperature maps, enhancing MR-guided procedures.

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Area of Science:

  • Magnetic Resonance Imaging
  • Medical Physics
  • Interventional Radiology

Background:

  • Accurate temperature monitoring is crucial for MR-guided thermal ablation procedures.
  • Low-field interventional MRI systems offer advantages but face challenges in real-time monitoring.
  • Proton resonance frequency (PRF) shift is a known method for MR thermometry.

Purpose of the Study:

  • To evaluate the feasibility of echo-shifted fast low-angle shot (FLASH) for temperature monitoring in a 0.2 T interventional MR scanner.
  • To assess the accuracy and speed of temperature mapping using this technique in various experimental settings.
  • To determine the potential of echo-shifted FLASH for improving MR-guided thermal therapies.

Main Methods:

  • Utilized a modified echo-shifted FLASH sequence on a 0.2 T interventional MR scanner.

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  • Performed experiments using polyacrylamide phantoms, ex vivo bovine liver, and an in vivo case.
  • Measured proton resonance frequency shifts to generate temperature maps with short acquisition times.

    • Main Results:

    • Achieved high signal-to-noise ratio for accurate temperature maps with scan times as short as 3-5 seconds.
    • Observed PRF shifts of -0.0072 ppm/°C in phantoms (±2.5°C uncertainty) and -0.0086 ppm/°C in ex vivo liver (±1°C uncertainty).
    • Demonstrated viability of echo-shifted FLASH for low-field temperature monitoring, despite reduced sensitivity compared to 1.5 T systems.

    Conclusions:

    • Echo-shifted FLASH is a feasible and effective method for real-time temperature monitoring in low-field interventional MR systems.
    • The improved temporal resolution allows for more accurate monitoring of interstitial ablation during MR-guided procedures.
    • This technique holds promise for enhancing the safety and efficacy of thermal therapies.