Gating of afferent input by a central pattern generator
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Updated: Oct 24, 2026

P50 Sensory Gating in Infants
Published on: December 26, 2013
1Neurobiology Program, Department of Biological Sciences, Ohio University, Athens, Ohio 45701, USA.
Abstract:
Intracellular recordings from the sole proprioceptor (the oval organ) in the crab ventilatory system show that the nonspiking afferent fibers from this organ receive a cyclic hyperpolarizing inhibition in phase with the ventilatory motor pattern. Although depolarizing and hyperpolarizing current pulses injected into a single afferent will reset the ventilatory motor pattern, the inhibitory input is of sufficient magnitude to block afferent input to the ventilatory central pattern generator (CPG) for approximately 50% of the cycle period. It is proposed that this inhibitory input serves to gate sensory input to the ventilatory CPG to provide an unambiguous input to the ventilatory CPG.
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