[Correlation between intraoperative hemodynamic instability and postoperative renal dysfunction]

We studied whether postoperative renal dysfunction could be predicted from patient's preoperative conditions and the hemodynamics during operation. We evaluated intraoperative hemodynamics using mean value and coefficient of variation (CV) of heart rate and blood pressure during operation. Patients at high risk for renal damage were (1) elderly patients, (2) patients with pre-existing renal disease, (3) patients receiving cancer chemotherapy, and (4) patients having emergency surgery. We did not find a positive correlation between renal dysfunction and hypotension during operation. Large changes of CV of systolic pressure and diminutive changes of CV of diastolic pressure were associated with increased risk of postoperative renal dysfunction. It was difficult to predict postoperative renal complications only with patient's preoperative conditions and the hemodynamics during operation in this study.