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Central serous chorioretinopathy: bilateral multifocal electroretinographic abnormalities
1Department of Ophthalmology, Stanford University Medical Center, Calif 94305-5308, USA. marmor@stanford.edu
Archives of Ophthalmology (Chicago, Ill. : 1960)
|February 26, 1999
Summary
Central serous chorioretinopathy causes widespread retinal dysfunction in both eyes, even beyond detachment areas. Multifocal electroretinograms (MERGs) may predict susceptibility to this condition.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Electrophysiology
Background:
- Central serous chorioretinopathy (CSC) is a condition affecting the macula.
- Retinal function in CSC is not fully understood, particularly in fellow eyes.
Purpose of the Study:
- To evaluate topographical retinal function in CSC patients.
- To compare affected and fellow eyes using multifocal electroretinograms (MERGs).
Main Methods:
- MERGs were recorded from 6 CSC patients and 5 controls.
- Responses were analyzed in rings from the foveal center.
- Full-field electroretinograms (ERGs) were also performed on two patients.
Main Results:
- MERGs showed reduced function in detachment areas and beyond in affected eyes.
- Fellow eyes also exhibited reduced MERG responses throughout the posterior pole.
- Full-field ERGs were normal, indicating localized functional deficits.
Conclusions:
- CSC involves extensive retinal functional disturbance in both eyes.
- Findings suggest underlying diffuse or systemic pathology, not just localized leakage.
- MERG may serve as a clinical marker for CSC susceptibility.