Related Experiment Video

Updated: Aug 24, 2026

Intravital Microscopy of the Inguinal Lymph Node
07:34

Intravital Microscopy of the Inguinal Lymph Node

Published on: April 4, 2011

Regional blood flow to the lymph node during the immune response

P G Herman, D Lyonnet, R Fingerhut

    Lymphology
    |September 1, 1976
    PubMed

    In 62 New Zealand white rabbits the regional blood flow to the popliteal lymph node was determined using the microsphere distribution and the Rb86C1 indicator methods. In 20 animals local immune response was induced with typhoid O antigen and in 7 with bovine serum albumin. The regional blood flow of the popliteal lymph node was 0.57 ml/gm/min. During the immune response the blood flow and weight changes were strictly proportional. The lymph node has the capacity to maintain its blood flow, even following significant enlargement.

    More Related Videos

    Visualizing Lymph Node Structure and Cellular Localization using Ex-Vivo Confocal Microscopy07:40

    Visualizing Lymph Node Structure and Cellular Localization using Ex-Vivo Confocal Microscopy

    Published on: August 9, 2019

    Blocking Lymph Flow by Suturing Afferent Lymphatic Vessels in Mice05:59

    Blocking Lymph Flow by Suturing Afferent Lymphatic Vessels in Mice

    Published on: May 14, 2020

    Related Concept Videos

    Introduction to Lymphatic and Immune System01:23

    Introduction to Lymphatic and Immune System

    Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
    The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are born...
    Functions of the Lymphatic and Immune System01:28

    Functions of the Lymphatic and Immune System

    The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
    The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
    Lymphatic Vessels and Lymph Transport01:16

    Lymphatic Vessels and Lymph Transport

    Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
    This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.
    Lymphoid Cells and Tissues01:18

    Lymphoid Cells and Tissues

    Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
    Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
    Secondary Lymphoid Organs01:15

    Secondary Lymphoid Organs

    Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
    The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
    Development of the Lymphatic System01:15

    Development of the Lymphatic System

    The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
    The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...