[Effects of amitryptyline in the development of depression]

Considering depression as a condition that damages physical, mental and social wellbeing, in the individual as well as in the community, research was made in the evolution of symptoms of depressive syndromes of 33 subjects, when treated with amytryptiline compounds. Treatment was begun with 25 mg daily and increased to 150 mg; doses were divided to avoid somnolence, and maintained for 8 to 14 weeks. Depressive syndromes showed improvement in 100% of cases, with resolution of clinical depression in 80%.