[Amitriptyline in the treatment of depression]

Oral tryptyline was evaluated clinically in the treatment of 14 male and 16 female patients; ages were 17 to 52 years the males and 32 to 59 years the females. Four had had no prior antidepressive treatment and the rest had had medication with poor to no results. The study ran for 12 weeks, with 15 patients showing improvement by the fourth week, 8 by the fifth week, 1 by the sixth; 5 showed no change. Side effects disappeared adjusting the dosage. Seventeen patients showed total improvement, 8 moderate improvement and 5 showed no change.