Diamine auxotrophy in a eukaryotic parasite

Fexinidazole for the treatment of human African trypanosomiasis.

Drugs of today (Barcelona, Spain : 1998)·2019

Rational design of peptide-based inhibitors of trypanothione reductase as potential antitrypanosomal drugs.

Amino acids·2013

Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony.

Parasitology·2007

Why are many mRNAs translated to the vicinity of mitochondria: a role in protein complex assembly?

Gene·2005

Peptoid inhibition of trypanothione reductase as a potential antitrypanosomal and antileishmanial drug lead.

Amino acids·2002

Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine.

Bioorganic & medicinal chemistry letters·2001

Escape from X-chromosome inactivation: from gene discovery to regulatory mechanisms.

Biochemical Society transactions·2026

Nitroxoline revisited: antibacterial mechanisms, spectrum, and therapeutic potential of an old drug in the era of antimicrobial resistance.

Biochemical Society transactions·2026

Beyond the scaffold: extracellular matrix uptake in breast cancer.

Biochemical Society transactions·2026

TDP-43 proteinopathy as a biomarker and therapeutic target in amyotrophic lateral sclerosis.

Biochemical Society transactions·2026

Advancing the monitoring of organelle contact sites in vitro and in vivo.

Biochemical Society transactions·2026

Mechanisms influencing transient cytoplasmic protein targeting to intracellular lipid droplets.

Biochemical Society transactions·2026

Microbiota-gut-brain axis imbalance: a promising therapeutic target for preserving brain health in high-altitude environment.

Frontiers in neuroscience·2026

A dual-prototype morphological topology evolution network for clinically oriented brain tumor MRI segmentation.

Frontiers in oncology·2026

Nose-to-brain delivery of candesartan-loaded nanoemulsion: brain biodistribution and neurobehavioral outcomes in controlled cortical impact-induced traumatic brain injury.

Inflammopharmacology·2026

Enhancing brain delivery of tegaserod for Alzheimer's disease: a pharmaceutical comparison of two nanocarrier-based strategies.

International journal of pharmaceutics·2026

Design and in silico validation of donor DNA for RNA-guided recombinase-mediated knockout of mstnb gene in Labeo rohita.

PloS one·2026

Prediction of migraine treatment response with clinical and genetic data: A machine learning analysis of the HUNT study.

Cephalalgia : an international journal of headache·2026

Related Experiment Videos

Diamine auxotrophy in a eukaryotic parasite

Related Concept Videos

Fexinidazole for the treatment of human African trypanosomiasis.

Rational design of peptide-based inhibitors of trypanothione reductase as potential antitrypanosomal drugs.

Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony.

Why are many mRNAs translated to the vicinity of mitochondria: a role in protein complex assembly?

Peptoid inhibition of trypanothione reductase as a potential antitrypanosomal and antileishmanial drug lead.

Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine.

Escape from X-chromosome inactivation: from gene discovery to regulatory mechanisms.

Nitroxoline revisited: antibacterial mechanisms, spectrum, and therapeutic potential of an old drug in the era of antimicrobial resistance.

Beyond the scaffold: extracellular matrix uptake in breast cancer.

TDP-43 proteinopathy as a biomarker and therapeutic target in amyotrophic lateral sclerosis.

Advancing the monitoring of organelle contact sites in vitro and in vivo.

Mechanisms influencing transient cytoplasmic protein targeting to intracellular lipid droplets.

Microbiota-gut-brain axis imbalance: a promising therapeutic target for preserving brain health in high-altitude environment.

A dual-prototype morphological topology evolution network for clinically oriented brain tumor MRI segmentation.

Nose-to-brain delivery of candesartan-loaded nanoemulsion: brain biodistribution and neurobehavioral outcomes in controlled cortical impact-induced traumatic brain injury.

Enhancing brain delivery of tegaserod for Alzheimer's disease: a pharmaceutical comparison of two nanocarrier-based strategies.

Design and in silico validation of donor DNA for RNA-guided recombinase-mediated knockout of mstnb gene in Labeo rohita.

Prediction of migraine treatment response with clinical and genetic data: A machine learning analysis of the HUNT study.

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Diamine auxotrophy in a eukaryotic parasite

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