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Related Experiment Videos

An alternate method for calibrating the thromboelastograph.

S E McNulty1, D P Maguire, L D Arai

  • 1Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA.

Journal of Cardiothoracic and Vascular Anesthesia
|February 27, 1999
PubMed
Summary
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Conductive gel offers a reliable method for calibrating the Thrombelastograph, ensuring functional status checks in operating rooms. This practical approach is more efficient than using blood analogs for device calibration.

Area of Science:

  • Medical Device Calibration
  • Point-of-Care Diagnostics
  • Hemostasis Monitoring

Background:

  • The Thrombelastograph (TEG) is crucial for assessing hemostasis.
  • Accurate calibration is essential for reliable TEG results.
  • Standard calibration methods may be time-consuming or impractical in certain settings.

Purpose of the Study:

  • To evaluate common operating room substances for Thrombelastograph calibration.
  • To determine the most reproducible substance for functional status checks.
  • To assess the clinical relevance of gel-based calibration.

Main Methods:

  • Prospective, controlled comparison of six operating room substances.
  • Thromboelastography analysis for 3 minutes on each substance (n=60 per substance).

Related Experiment Videos

  • Evaluation of amplitude variability and reproducibility.

    • Main Results:

    • Ointments and creams showed high amplitude variability (>10 mm).
    • Conductive gel demonstrated the most reproducible tracing (mean amplitude 62.5 ± 1.1 mm).
    • Significant correlation between gel viscosity and deflection amplitude (R²=0.97, p<0.0001).

    Conclusions:

    • Conductive gel is a practical and effective substance for rapid Thrombelastograph functional checks.
    • Gel calibration offers a clinically relevant and more practical alternative to blood analogs.
    • This method enhances operational readiness of the Thrombelastograph.