[Pfeifer-Weber-Christian disease with a 20-year course]

The reported case belongs in rarely occurring general diseases running a chronic relapsing course. The case is uncommon because of not only general affection of the adipose tissue presenting with immunologic inflammation, but also of the development of manifest abnormal changes in the internals, amyloidosis in particular. 20-year follow-up of the patient suggests that the evolution of the above pathological processes might be caused by both the nature of the underlying disease and a long-continued administration of corticosteroids.