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Updated: Aug 12, 2026

A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
Published on: January 11, 2018
Osteoarthritis and abnormal bone marrow of the mandibular condyle
T Sano1, P L Westesson, T A Larheim
1Department of Oral Radiology, Showa University School of Dentistry, Tokyo, Japan.
Objective:
The purpose of this study was to analyze the relationship between abnormal bone marrow of the mandibular condyle and osteoarthritis.
Study Design:
The relationship between abnormal bone marrow and osteoarthritis of the mandibular condyle was analyzed in magnetic resonance images of the temporomandibular joints of 74 patients. Thirty-seven patients had magnetic resonance evidence of abnormal bone marrow, and 37 control patients had magnetic resonance images with normal bone marrow.
Results:
Fifteen of 37 patients with magnetic resonance evidence of abnormal bone marrow had no magnetic resonance evidence of osteoarthritis; the other 22 patients had both abnormal bone marrow and osteoarthritis.
Conclusions:
Abnormal bone marrow of the mandibular condyle can occur separately from osteoarthritis; nearly one half of the joints with magnetic resonance evidence of abnormal bone marrow did not have any evident osteoarthritis. Abnormal bone marrow may therefore initially represent a separate disease entity. Over time, secondary osteoarthritis probably develops in joints with initial bone marrow abnormalities.
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