Related Experiment Videos
The inhibitory effect of IgM RF on the release of lysosomal substances
Scandinavian Journal of Rheumatology
|January 1, 1976
Isolated IgM RF inhibited the IgG-induced release of lysosomal substances, measured as 'large molecular size vitamin B12-binding protein' (LBP) and beta-glucronidase, from separated human granulocytes. The effect was most marked when cytochalasin B was added to the experimental system. The results indicate that the RFs interact with the granulocyte binding region of IgG.
Isolated IgM RF inhibited the IgG-induced release of lysosomal substances, measured as 'large molecular size vitamin B12-binding protein' (LBP) and beta-glucronidase, from separated human granulocytes. The effect was most marked when cytochalasin B was added to the experimental system. The results indicate that the RFs interact with the granulocyte binding region of IgG.