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Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development
I Hermans-Borgmeyer1, G Hermey, A Nykjaer
1Zentrum für Molekulare Neurobiologie, University of Hamburg, Martinistr. 52, D-20246, Hamburg, Germany. hermans@uke.uni-hamburg.de
Brain Research. Molecular Brain Research
|March 5, 1999
Abstract:
Recently, sortilin a non G-protein-coupled receptor has been identified as the 100-kDa neurotensin receptor. In this paper we describe the expression of its gene during mouse embryonal development. We show that the nervous system is the main location of sortilin gene expression and that with ongoing development the forebrain exhibits the highest accumulation of transcripts.