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Colorectal neoplasms: a retrospective study.
1Department of Morbid Anatomy, College of Medicine, University of Lagos, Nigeria.
East African Medical Journal
|March 5, 1999
Summary
This study of colorectal neoplasms found a male predominance and peak incidence in the fifth decade. Rectal tumors were most common, with advanced stages often presenting late, particularly mucinous adenocarcinoma.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Colorectal neoplasms represent a significant health concern globally.
- Understanding the epidemiology and clinical presentation of these tumors is crucial for early detection and improved patient outcomes.
Purpose of the Study:
- To analyze the demographic, clinical, and pathological features of colorectal neoplasms.
- To identify patterns in tumor location, morphology, and stage at presentation.
Main Methods:
- Retrospective analysis of 254 cases of colorectal neoplasms.
- Data collection included patient demographics, tumor site, histological type, and presenting stage.
Main Results:
- A male predominance was observed in both benign (M:F 4.6:1) and malignant (M:F 1.1:1) neoplasms, with peak incidence in the fifth decade.
- The rectum was the most common site for both benign (75%) and malignant (63%) neoplasms.
- Adenocarcinoma was the most frequent malignancy (90%), with mucinous variants often presenting at advanced stages, potentially due to late patient presentation.
Conclusions:
- Colorectal neoplasms exhibit a male predominance and commonly affect the rectum.
- Histopathological patterns differ by tumor location, and advanced stage at presentation is a concern, highlighting the need for increased awareness and earlier medical consultation.