Related Experiment Video
Updated: Aug 4, 2026

08:12
Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
[Kidney donation by a 'non-heart-beating' donor from an ethical perspective]
H B van Wezel1, A J Hoitsma, J A van der Vliet
1Afd. Nierziekten, Academisch Ziekenhuis, Nijmegen.
Nederlands Tijdschrift Voor Geneeskunde
|March 5, 1999
Summary
Kidney donation is possible in asystolic patients using the non-heart-beating (NHB) procedure. A developed protocol addresses ethical concerns and ensures prudent NHB kidney donation practices.
Area of Science:
- Nephrology
- Transplantation Surgery
- Medical Ethics
Background:
- Non-heart-beating (NHB) kidney donation allows organ procurement from asystolic patients.
- The procedure involves in situ perfusion of kidneys via femoral artery catheterization and cold fluid flushing.
Discussion:
- NHB donation raises ethical questions regarding death definition, team responsibility separation, family care, and impact on patient treatment.
- Extensive discussions with the Medical Ethics Committee of the University Hospital Nijmegen were conducted.
Key Insights:
- A protocol for NHB kidney donation has been established.
- The protocol aims to meet guarantees for prudent procedure and ethical considerations.
Outlook:
- Implementation of this protocol can facilitate safe and ethical NHB kidney donation.
- Further refinement of ethical guidelines and procedural standards in organ donation is anticipated.
Related Concept Videos
Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

