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Updated: Aug 28, 2026

Simultaneous Electrophysiological Recording and Micro-injections of Inhibitory Agents in the Rodent Brain
Published on: July 7, 2015
Reversible inactivation of subcortical sites by drug injection
1Department of Psychology, University of Illinois, Champaign 61820, USA. jmalpeli@uiuc.edu
Abstract:
Reversible inactivation of subcortical targets by means of drug injections has been a powerful tool for revealing the contributions of discrete brain structures to behavior and the functional organization of the brain. This paper is intended to provide practical advice on this approach, including the choice of drug, means of delivering drugs, strategies for evaluating the action of injected drugs, and the application of this method to experiments with awake animals.
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