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Related Concept Videos

Overview of the Skull01:08

Overview of the Skull

The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws.
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
Cranial Bones: Superior and Posterior View01:14

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Cranial Bones: Lateral View01:27

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The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Sutures of the Skull01:22

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Muscles for Facial Expressions

The craniofacial muscles are a collection of approximately 20 thin skeletal muscles situated beneath the skin of the face and scalp. These muscles, primarily responsible for the vast array of human facial expressions, originate from the bones or fibrous structures of the skull and extend outwards to connect with the skin. While most skeletal muscles in the body are enveloped in thick fascia, facial muscles generally have a more delicate fascial covering, with the buccinator muscle being a...
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Cranial Nerves: Overview and Anatomy

The cranial nerves are an important part of the complex network of nerves in the human body. These nerves emerge directly from the brain and are responsible for transmitting essential information between the brain and various parts of the head and neck. There are 12 pairs of cranial nerves, systematically numbered using Roman numerals from I to XII, beginning from the anterior and moving to the posterior of the brain. Each cranial nerve is uniquely identified by names that reflect its function...

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Quantification of Orofacial Phenotypes in Xenopus
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Is craniofacial morphology in Apert and Crouzon syndromes the same?

S Kreiborg1, M M Cohen

  • 1Department of Pediatric Dentistry and Clinical Genetics, University of Copenhagen, Denmark.

Acta Odontologica Scandinavica
|March 5, 1999
PubMed
Summary
This summary is machine-generated.

Craniofacial development differs between Apert and Crouzon syndromes. Apert syndrome generally shows more severe abnormal craniofacial morphology compared to Crouzon syndrome, affecting multiple skull and facial structures.

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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
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Area of Science:

  • Craniofacial Development
  • Genetics
  • Medical Research

Background:

  • Apert syndrome and Crouzon syndrome are craniosynostosis disorders.
  • Previous research has explored their craniofacial development.
  • Understanding differences is crucial for diagnosis and treatment.

Purpose of the Study:

  • To review existing research on craniofacial development in Apert and Crouzon syndromes.
  • To present new roentgencephalometric data.
  • To compare craniofacial development between Apert and Crouzon syndromes.

Main Methods:

  • Literature review of previous studies.
  • Collection and analysis of new roentgencephalometric data.
  • Comparative analysis of craniofacial structures.

Main Results:

  • Craniofacial development is not identical in Apert and Crouzon syndromes.
  • Significant differences observed in calvaria, cranial base, orbit, maxilla, zygoma, incisal occlusion, and soft tissue profile.
  • Apert syndrome exhibited more severe craniofacial abnormalities than Crouzon syndrome.

Conclusions:

  • Craniofacial development pathways diverge between Apert and Crouzon syndromes.
  • Distinct morphological patterns necessitate tailored clinical management.
  • Further research can refine understanding and treatment strategies.