Growth sites and growth mechanisms at risk in cleft lip and palate

H Friede1

  • 1Department of Orthodontics, Faculty of Odontology, Göteborg University, Sweden.

Insights

Facial cleft surgery can impact midfacial growth, particularly due to scar tissue from palatal repair. Minimizing scar tissue and protecting the vomero-(pre)maxillary suture are key to preserving normal maxillary development in cleft patients.

Area of Science:

  • Craniofacial biology
  • Pediatric surgery
  • Orthodontics

Background:

  • Facial clefts disrupt normal craniofacial development, affecting the nose, lip, and jaw.
  • Surgical interventions aim to correct these deformities but can inadvertently impede midfacial growth.
  • Understanding growth mechanisms is crucial for optimizing treatment outcomes.

Purpose of the Study:

  • To review aspects of midfacial growth in normal and cleft subjects.
  • To elucidate the impact of surgical interventions on maxillary development.
  • To discuss strategies for mitigating negative growth effects.

Main Methods:

  • Review of literature on craniofacial growth and cleft repair.
  • Analysis of growth influences on the maxilla and dentoalveolar structures.
  • Discussion of scar tissue effects and potential preventative measures.

Main Results:

  • Lip surgery generally does not affect maxillary elongation, but palatal repair scar tissue can impede growth.
  • Scar tissue from palatal repair can negatively affect periosteal growth and dentoalveolar development.
  • Vomero-(pre)maxillary suture integrity is vital for normal midfacial growth and should be preserved during early surgery.

Conclusions:

  • Palatal scar tissue is a significant factor limiting midfacial growth post-cleft surgery.
  • Surgical techniques should aim to minimize scar formation and protect critical growth sutures.
  • Further research into scar reduction methods could improve long-term functional and aesthetic results in cleft patients.