Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cell cycle and sporulation in Bacillus subtilis.

P A Levin1, A D Grossman

  • 1Department of Biology, Building 68-530, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Current Opinion in Microbiology
|March 6, 1999
PubMed
Summary

Bacillus subtilis cell division and chromosome segregation are key to regulating its cell cycle and development. These processes are essential for entering sporulation and establishing specific gene expression patterns.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Visualization of mismatch repair in bacterial cells.

Molecular cell·2002
Same author

In vivo effects of sporulation kinases on mutant Spo0A proteins in Bacillus subtilis.

Journal of bacteriology·2001
Same author

Polymer stability plays an important role in the positional regulation of FtsZ.

Journal of bacteriology·2001
Same author

The extrusion-capture model for chromosome partitioning in bacteria.

Genes & development·2001
Same author

Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.

Journal of bacteriology·2001
Same author

Replication initiation proteins regulate a developmental checkpoint in Bacillus subtilis.

Cell·2001

Area of Science:

  • Microbiology
  • Molecular Biology
  • Cell Biology

Background:

  • Cell division and chromosome dynamics are crucial for bacterial growth and development.
  • Bacillus subtilis utilizes complex regulatory mechanisms for cell cycle control.
  • Sporulation in B. subtilis involves intricate modifications of cell division and DNA segregation.

Purpose of the Study:

  • To elucidate the role of cell division and chromosome partitioning in Bacillus subtilis.
  • To understand cell cycle regulation during bacterial growth and development.
  • To investigate how DNA integrity and segregation signals modulate sporulation entry.

Main Methods:

  • Analysis of cell division processes in Bacillus subtilis.
  • Studies on chromosome orientation and segregation mechanisms.

Related Experiment Videos

  • Investigation of signaling pathways regulating sporulation.

    • Main Results:

    • Cell division and chromosome dynamics provide insights into B. subtilis cell cycle regulation.
    • Signals related to DNA integrity, replication, and segregation modulate sporulation.
    • B. subtilis modifies cell division and DNA segregation for cell-type-specific gene expression during sporulation.

    Conclusions:

    • Cell cycle regulation is integral to Bacillus subtilis development and sporulation.
    • Proper DNA segregation and cell division are critical for initiating sporulation.
    • Modifications in these processes establish distinct gene expression profiles for sporulation.