Related Experiment Videos
A murine model of renal abscess formation
G M Mussalli1, S R Brunnert, E Hirsch
1Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.
Clinical and Diagnostic Laboratory Immunology
|March 6, 1999
Abstract:
We developed a murine model of kidney abscess by direct renal injection of either Escherichia coli (1 x 10(6) to 7 x 10(6) organisms) or sterile medium. Bacterial infection produced renal abscesses, bacteremia, and late-onset leukocytosis in all animals. Controls were unaffected. This model may be useful for the study of various sequelae of kidney infection.