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[Carcinoid tumors].

V B Simonenko, P A Dugin, M A Makanin

    Klinicheskaia Meditsina
    |March 6, 1999
    PubMed
    Summary
    This summary is machine-generated.

    Carcinoid tumors, new growths from neuroendocrine cells, present asymptomatically or with mass symptoms. Carcinoid syndrome with liver metastases indicates a late-stage diagnosis.

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    Area of Science:

    • Oncology
    • Endocrinology
    • Gastroenterology

    Context:

    • Carcinoid tumors originate from neuroendocrine cells.
    • This study analyzed 11 patients with histologically verified carcinoid tumors.
    • Carcinoid tumors are more common than typically diagnosed, estimated at 0.1-0.5% of all tumors.

    Purpose:

    • To describe the clinical variants of carcinoid tumors observed in a cohort of 11 patients.
    • To highlight the diagnostic challenges and late-stage presentation of carcinoid syndrome.

    Summary:

    • Observed variants included asymptomatic cases, mass-related symptoms (intestinal ileus, appendicitis-like), and carcinoid syndrome with hepatic metastases.
    • Carcinoid syndrome, characterized by liver metastases, was identified with unknown primary sites, lung, or pancreas origins.

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  • Diagnosis of carcinoid tumors is often delayed until the carcinoid syndrome manifests, indicating advanced disease with significant tumor burden and liver involvement.

    • Impact:

    • Understanding these clinical variants can improve early detection and diagnosis of carcinoid tumors.
    • Recognizing the signs of carcinoid syndrome is crucial for timely intervention, even with unknown primary tumors.
    • This research underscores the importance of considering carcinoid tumors in differential diagnoses, especially when symptoms are non-specific or suggestive of advanced malignancy.