A study of human rabies immune globulin manufactured by the Thai Red Cross

This is a prospective post marketing study of 4496 patients presenting with severe animal bites in a canine rabies endemic region. They received human rabies immune globulin manufactured from volunteer blood donors at the National Blood Center of the Thai Red Cross Society at Bangkok. All patients also received a full course of tissue culture rabies vaccine. Only three subjects reported an adverse reaction (redness and itching at the immune globulin injection sites). None of the patients died during the subsequent 18 month follow up period.