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Published on: August 12, 2020
Etiology of septic arthritis in children: an update for the 1990s
1Department of Pediatrics, Washington University School of Medicine, St. Louis 63110-1077, USA. luhmann_j@kidsA1.wustl.edu
Insights
Septic arthritis in children is now frequently caused by Staphylococcus aureus, not Haemophilus influenzae type B, following immunization guidelines. Early diagnosis remains a challenge, with many cases initially misdiagnosed.
Area of Science:
- Pediatric Infectious Diseases
- Rheumatology
- Microbiology
Background:
- Septic arthritis is a serious joint infection in children.
- Haemophilus influenzae type B (Hib) was a leading cause before widespread immunization.
- Etiology may have shifted following Hib vaccination campaigns.
Purpose of the Study:
- To determine the current causes of septic arthritis in children.
- To assess the impact of Hib immunization on the etiology of pediatric septic arthritis.
Main Methods:
- Retrospective chart review of pediatric septic arthritis cases (ICD-9: 711).
- Study period: January 1991 to December 1996 at St. Louis Children's Hospital.
- Analysis of patient demographics, causative organisms, and diagnostic accuracy.
Main Results:
- Sixty-four children diagnosed with septic arthritis were identified.
- Staphylococcus aureus was the most common pathogen (10 isolates).
- Only one case of Haemophilus influenzae type B was identified in an unimmunized child.
Conclusions:
- Staphylococcus aureus is a predominant pathogen in pediatric septic arthritis.
- Haemophilus influenzae type B is no longer the leading cause in immunized children.
- Septic arthritis in children is often misdiagnosed initially.
Objective:
To establish the etiology of septic arthritis in children after implementation of HIB immunization guidelines.
Methods:
A retrospective review of all charts with a discharge diagnosis of septic arthritis (ICD-9: 711) from January 1991 to December 1996 at St. Louis Children's Hospital was conducted.
Results:
Sixty-four patients (male = 58%) were identified, whose median age was 6.0 years. Twenty-one children (33%) were misdiagnosed on initial presentation. An organism was isolated in 38 (59%) of cases. The predominant organisms were Staphylococcus aureus (10 isolates), Group A Streptococcus (4), Enterobacter species (4), Kingella kingae (3), Neisseria meningitides (3), Streptococcus pneumoniae (2), Neisseria gonorrhoeae (2), Candida (2), Staphylococcus epidermidis (2). The only isolate of Haemophilus influenzae type B was in 1992 in an unimmunized 14 month old.
Conclusions:
These data confirm Staphylococcus aureus as a frequent pathogen and suggest that H influenzae type B is no longer the predominant isolate in young children with septic arthritis. In addition, early septic arthritis in children is frequently misdiagnosed on initial evaluation.
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