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Updated: Jul 12, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
Management of allergic rhinitis with a combination antihistamine/anti-inflammatory agent
1Division of Allergy and Immunology and the Department of Pediatrics, University of Tennessee School of Medicine, Knoxville, USA.
Abstract:
Azelastine nasal spray is a topical antihistamine treatment for the symptoms of seasonal allergic rhinitis. Besides histamine antagonism, azelastine affects other chemical mediators of the inflammatory response including leukotrienes and kinins. This article reviews and discusses the antihistaminic and anti-inflammatory properties of azelastine and the results of pharmacokinetic studies and controlled clinical trials.
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