Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ventilatory care in status asthmaticus.

R J Smyth1

  • 1Department of Anaesthesia, York County Hospital, Newmarket, Canada.

Canadian Respiratory Journal
|March 10, 1999
PubMed
Summary

Severe asthma exacerbations can necessitate mechanical ventilation. Noninvasive ventilation strategies, like pressure support ventilation, offer effective breathing support while minimizing risks in patients with severe bronchoconstriction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determinants of entry cofactor utilization and tropism in a dualtropic human immunodeficiency virus type 1 primary isolate.

Journal of virology·1998
Same author

Abortive infection in HeLaCD4 cells by a primary HIV type 1 isolate: implications for differential host cell tropism.

AIDS research and human retroviruses·1997
Same author

Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation.

Journal of virology·1997
Same author

Initial clinical experience with the Ahmed Glaucoma Valve implant in pediatric patients.

Archives of ophthalmology (Chicago, Ill. : 1960)·1997
Same author

Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity.

Cell·1996
Same author

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.

Nature·1996

Area of Science:

  • Pulmonology
  • Critical Care Medicine

Background:

  • Asthma exacerbations present significant morbidity and mortality risks.
  • Some severe cases require mechanical ventilation when standard therapies fail.

Purpose of the Study:

  • To explore novel ventilatory support strategies for severe asthma.
  • To evaluate the efficacy of noninvasive ventilation in severe bronchoconstriction.

Main Methods:

  • Utilizing noninvasive ventilation, specifically pressure support ventilation.
  • Carefully balancing respiratory frequency, tidal volume, and inspiratory flow rates.
  • Considering adjuvant therapies like inhaled anesthetics and bronchoalveolar lavage.

Main Results:

  • Noninvasive ventilation provides effective support even with severe bronchoconstriction.
  • Pressure support ventilation mitigates barotrauma and reduces work of breathing.
  • Auto positive end-expiratory pressure management is critical.

Conclusions:

  • Noninvasive ventilation is a viable option for severe asthma requiring mechanical support.
  • Optimized ventilatory parameters and adjuvant therapies can improve outcomes.

Related Experiment Videos