Related Experiment Video
Updated: Aug 7, 2026
Epidural Intracranial Pressure Measurement in Rats Using a Fiber-optic Pressure Transducer
Published on: April 25, 2012
Intraocular pressure measurement in the conscious rat
C L Cabrera1, L A Wagner, M A Schork
1Department of Physiology, the Medical School, University of Michigan, Ann Arbor, USA.
Purpose:
To develop a method for measurement of intraocular pressure in conscious, unsedated rats. METHODS. The animal was gently held with a thick fabric mitten, topical anesthetic drops were instilled and the Tono-Pen was applied to the cornea.
Result:
Measurements in a total of 51 animals did not differ significantly among four strains studied: the overall mean intraocular pressure+/-standard deviation was 13.0+/-1.2 mm Hg. Several intraocular pressure tolerance limits were calculated from this conscious rat data to provide a baseline estimate for future studies.
Conclusions:
This measurement method in conscious rats may contribute to making this widely used laboratory animal available for intraocular pressure research.
