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Management of choroidal melanomas with linear accelerator-based stereotactic radiosurgery
S W Leung1, C Y Hsiung, H C Chen
1Department of Radiation Oncology, Chang Gung Memorial Hospital Kaohsiung Center and Chang Gung University, Taoyuan, Taiwan. qly@ma.ks.edu.tw
Purpose:
To discuss the technical aspect, dose prescription, clinical results, and biological responsiveness of linear accelerator-based stereotactic radiosurgery for choroidal melanoma.
Methods:
From March 1995 to December 1995, three choroidal melanoma patients were treated with Linac-based radiosurgery in our department. Two patients underwent one dose of radiosurgery with 18 and 20 Gy in single fraction, respectively. The third patient received two doses of radiosurgery with a total dose of 35 Gy.
Results:
Follow-up time ranged from 19 to 25 months (median: 24 months). One patient had near-total regression, while the other two patients had partial response on the last MR images. Visual acuity was deteriorated in all patients. One patient developed a radiation-induced cataract in the treated eye.
Conclusion:
Linac-based radiosurgery is technically feasible for management of choroidal melanoma. Although visual acuity was not improved in these patients, they appreciated the preserving of the eyeball without affecting their general appearance.