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Particle size distributions in mesh cuts and microscopically estimated volumetric shape factors
1School of Pharmacy, University of Wisconsin, Madison 53706, USA.
Abstract:
When particle size distribution parameters are calculated from sieve analysis, it is generally assumed that the distribution within the particle cut is either linear, producing a mean particle size equal to the average of the mesh openings (1-3), or that a more proper number is the geometric mean of these two apertures. It is shown here that particles within a mesh cut are not linearly distributed, but rather may be normally, long-normally, or biphasic combinations of the two. Three compounds were examined in this fashion, and results are reported here.

