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Related Experiment Videos

Eyelid pruritus with intravenous morphine.

G Castaño1, C J Lyons

  • 1Department of Ophthalmology, British Columbia's Children's Hospital, University of British Columbia, Vancouver, Canada.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|March 11, 1999
PubMed
Summary

Identifying the cause of eyelid itching can be challenging, especially in young children. Persistent eye rubbing after leukemia treatment was linked to morphine administration, highlighting a crucial diagnostic consideration.

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Area of Science:

  • Ophthalmology
  • Hematology
  • Pediatrics

Background:

  • Eyelid pruritus (itching) diagnosis is complex, particularly in preverbal children.
  • Ocular symptoms like tearing, photophobia, or eye rubbing can indicate serious conditions such as leukemic infiltration or graft-versus-host disease.
  • Early identification and therapy are critical for managing these conditions.

Observation:

  • A case study involving a child who underwent bone marrow transplantation for leukemia is presented.
  • The child developed persistent eye rubbing following the transplantation procedure.

Findings:

  • Morphine administration was identified as the direct cause of the persistent eye rubbing symptom.
  • This finding suggests a potential adverse effect of morphine in post-transplant pediatric patients.

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Implications:

  • Clinicians should consider morphine as a potential cause of eye rubbing in pediatric patients, especially those who have undergone bone marrow transplantation.
  • This highlights the importance of thorough medication review and symptom correlation in diagnosing pediatric ocular complaints.
  • Further research may be warranted to explore the mechanism and prevalence of morphine-induced eye rubbing in this population.