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[Pleural amyloidosis].

Y Sun1, W Xu, W Luo

  • 1Department of Respiratory Medicine, Peking Union Medical College Hospital, Beijing.

Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases
|August 1, 1997
PubMed
Summary
This summary is machine-generated.

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Systemic amyloidosis frequently causes pleural effusion, a condition often overlooked. Diagnosis is confirmed via percutaneous pleural biopsy with Congo red staining, especially in patients with multiorgan disease.

Area of Science:

  • Medicine
  • Pathology
  • Pulmonology

Background:

  • Pleural effusion is a common clinical finding with a broad differential diagnosis.
  • Systemic amyloidosis is a rare but serious condition that can affect multiple organs.

Observation:

  • This study retrospectively analyzed 15 cases of systemic amyloidosis to determine the incidence and characteristics of pleural effusion.
  • Seven cases (47%) of systemic amyloidosis presented with pleural effusion.

Findings:

  • Four of the seven cases with pleural effusion were confirmed to have pleural amyloidosis via positive Congo red staining on percutaneous pleural biopsy specimens.
  • Pleural involvement in systemic amyloidosis is more common than previously thought.

Implications:

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  • Systemic amyloidosis should be considered in the differential diagnosis of unexplained pleural effusion, particularly in patients with co-existing multiorgan involvement.
  • Percutaneous pleural biopsy with Congo red staining is a valuable diagnostic tool for pleural amyloidosis.